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HOMA-B Calculator

Measure your pancreatic beta cell function — your body's ability to produce and secrete insulin in response to glucose

Metabolic Relevance
HOMA-B = (20 × Fasting Insulin) / (Fasting Glucose − 3.5) reveals how hard your pancreas is working. While HOMA-IR shows insulin resistance, HOMA-B shows insulin production capacity. Together they provide the complete picture of glucose metabolism.

Recommended testing frequency:
Every 3-6 months alongside HOMA-IR, especially when monitoring metabolic interventions

Did you know?

High HOMA-B isn't always good! When combined with high HOMA-IR, it signals beta cell overcompensation — your pancreas is working overtime to maintain normal glucose. This is an early warning sign before diabetes develops.

HOMA-B naturally decreases on ketogenic diets because your body needs less insulin. Lower values in this context are expected and typically healthy.

Want to understand your result better?

Learn about interpretation, what affects your score, and evidence-based strategies to improve it.

Read the full guide

Evidence-Based

This calculator is based on peer-reviewed research validated across thousands of clinical studies.

View scientific references(1)

Medical Disclaimer

This calculator is for educational and informational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or other qualified health provider with any questions you may have regarding your health.

Why Optimal Thresholds Differ?

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Standard Medical

Conventional ranges (60-200% normal)

⚠️ Broad range misses early compensation patterns

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Research Consensus

Functional medicine targets (100-150% optimal)

Identifies beta cell strain before exhaustion

Metabolic Optimization

Low-carb adapted (80-120% expected)

🔬 Lower insulin needs = lower HOMA-B expected